Kyoto University · Institute for Life and Medical Sciences · 特定助教

Research keywordsToll like receptor 7・Toll like receptor 8・innate immune agonists・QSAR analysis・proteolytic autoinhibition・endogenous nucleosides・SARS CoV 2 spike conformations

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• A triggering structure of SARS-CoV-2 BA.2.86 spike upon ACE2 binding for receptor-binding domain up2024 · 2024年03月22日
• Structure-Based Design of Human TLR8-Specific Agonists with Augmented Potency and Adjuvanticity.Journal of medicinal chemistry,
• Structural basis of CpG and inhibitory DNA recognition by Toll-like receptor 9.Nature,
• Structural basis for receptor-binding domain mobility of the spike in SARS-CoV-2 BA.2.86 and JN.1Nature Communications,

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