Mie University · Graduate School of Medical Sciences · 助教

Research keywordsE3 ubiquitin ligases・deubiquitinases・ciliopathy・tumor angiogenesis・vascular endothelial cells・cancer stemness・Tie1 signaling・APJ signaling・antiangiogenic therapy・keratin intermediate filaments

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• Targeting E3 Ubiquitin Ligases and Deubiquitinases in Ciliopathy and Cancer. 2020.08 International journal of molecular sciences 212020 · 主な業績等
• Regulation of keratin 5/14 intermediate filaments by CDK1, Aurora-B, and Rho-kinase. 2018.04 Biochemical and biophysical research communications 498 544-5502018 · 主な業績等
• Visualization of Proliferative Vascular Endothelial Cells in Tumors inﾂVivo by Imaging Their Partner of Sld5-1 Promoter Activity. 2018.05 The American journal of pathology 188 1300-13142018 · 主な業績等
• Elevated expression of Tie1 is accompanied by acquisition of cancer stemness properties in colorectal cancer. 2017.06 Cancer medicine 6 1378-13882017 · 主な業績等

• ユビキチンシグナルによる一次線毛の形成機構と癌細胞増殖制御への標的化戦略
• Tie1細胞外ドメインによる腫瘍血管新生の制御機構の解明
• 筋肉障害及び修復におけるデスミンリン酸化の生理的・病態的意義の解明
• 一次線毛伸長誘導による脂肪細胞分化制御機構の理解

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