Mie University · Graduate School of Medical Sciences · 講師

Research keywordsCYP2A6 variants・CYP2B6 variants・polychlorinated biphenyls・hydroxylated metabolites・molnupiravir toxicity・reactive oxygen species・DNA damage・xenobiotic metabolism

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• Association between CYP2A6 genetic variants and serum concentrations of highly persistent OH-PCBs and their parent PCBs in humans.2026
• RNF213 Acts as a Molecular Switch for Cav-1 Ubiquitination and Phosphorylation in Human Cells2025
• Relationships among CYP2B6 genetic variants and serum levels of multiple polychlorinated biphenyls and hydroxylated metabolites in a Japanese population2025
• Reactive oxygen species-mediated cytotoxic and DNA-damaging mechanism of N4-hydroxycytidine, a metabolite of the COVID-19 therapeutic drug molnupiravir.2025

• RNF213遺伝子変異による小胞体ストレス亢進機構および心血管疾患における役割の解明2026
• 新たな小胞体ストレス制御因子としてのRNF213が糖尿病に果たす役割の解明2022
• もやもや病感受性遺伝子RNF213が炎症下で血管にあたえる影響の解明2019
• 新規周期性四肢疼痛症の加齢による寛解の分子機構解明と創薬への応用2015

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