Mie University · Biobank Center

Research keywordsnonalcoholic steatohepatitis・hepatic fibrosis・adipose tissue inflammation・lysosomal permeability・cytokeratin 18 biomarker・NKT17 cells・steatotic liver disease

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• Characterization and Proteome of Circulating Extracellular Vesicles as Potential Biomarkers for NASH.
• Induction of RNAi Responses by Short Left-Handed Hairpin RNAi Triggers
• siRNA delivery using peptide transduction domains
• Differential susceptibility of cells expressing allogeneic MHC or viral antigen to killing by antigen-specific CTL

• 脂肪肝における肝由来低エントロピー小胞による動脈硬化発症のメカニズムの解明
• エキソソーム型トロンボモジュリンによる敗血症治療
• 細胞選択的モデルが紐解くNAFLD/NASHに対するユビキチンプロテアーゼの役割
• 腸管粘膜の障害に焦点をあてた炎症性腸疾患の新規病態メカニズムの解明

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