Mie University · Graduate School of Medical Sciences · 特任助教

Research keywordsがんワクチン・がん免疫療法・腫瘍免疫学・免疫学・miRNAs・T細胞療法（TCR-T/CAR-T）・エクソソーム・ドラッグデリバリーシステム（DDS）

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• Potentiation of antitumor activity by antibody drugs and mushroom-derived beta-glucan in the natural killer cell-mediated tumoricidal activities against non-Hodgkin's B-cell lymphoma. Yoshiyuki Adachi, Fumiyasu Momose, Hiromi Momose, Rui Tada, Naohito Ohno,Int. J. Med. Mus., 12, 2022.2022 · 主な業績等
• Activated CD8+ T cell extracellular vesicles prevent tumour progression by targeting of lesional mesenchymal cells. Naohiro Seo, Yoshitaka Shirakura, Yoshiro Tahara, Fumiyasu Momose, Naozumi Harada, Hiroaki Ikeda, Kazunari Akiyoshi, Hiroshi Shiku. Nature Communications 9(1), 30 January,2018.2018 · 主な業績等
• Epirubicin, Identified Using a Novel Luciferase Reporter Assay for Foxp3 Inhibitors, Inhibits Regulatory T Cell Activity. Hajime Kashima, Fumiyasu Momose, Hiroshi Umehara, Nao Miyoshi, Naohisa Ogo, Daisuke Muraoka, Hiroshi Shiku, Naozumi Harada, Akira Asai. PLOS ONE 11(6), e0156643, 10 Jun,2016.2016 · 主な業績等
• Guanine-Rich Sequences Are a Dominant Feature of Exosomal microRNAs across the Mammalian Species and Cell Types. Fumiyasu Momose, Naohiro Seo, Yasushi Akahori, Shin-ichi Sawada, Naozumi Harada, Toru Ogura, Kazunari Akiyoshi, Hiroshi Shiku. PLOS ONE 11(4), e0154134-e0154134, 21 April,2016.2016 · 主な業績等

• hybrid-TCR法によるがん治療法の検討
• ヒアルロン酸誘導体がんワクチンのメモリーT細胞誘導作用とがん再発抑制機序の解明
• CpGによる活性化T細胞エクソソームを介したがん悪性化制御作用及び分子機構の解明
• がん間質間葉系細胞を傷害するmiRNA含有エクソソームによるがんの浸潤・転移阻害剤 の開発

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