Mukogawa Women's University · Faculty of Pharmaceutical Sciences · 准教授

Research keywordsneuroprotection・Nrf2 activators・cerebral ischemia・Parkinson disease・amyloid beta・tau phosphorylation・zebrafish screening・chalcone derivatives

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• Isolation and Purification of Harpagogenin as an Nrf2–ARE Activator from the Tubers of Chinese Artichoke (Stachys sieboldii)2023
• Establishing a high throughput drug screening system for cerebral ischemia using zebrafish larvae.2021
• [Donepezil Reduces Amyloid Precursor Protein Endocytosis by Resulting from Increase in the Expression of Sorting Nexin Protein 33].2021
• Protective effects of Nrf2-ARE activator on dopaminergic neuronal loss in Parkinson disease model mice: Possible involvement of heme oxygenase-1.2020

• アルツハイマー病の治療・予防薬開発に向けた新規創薬ターゲットの探索2022
• 神経保護シグナルとタウリン酸化制御の解析に基づく新規アルツハイマー病治療薬開発2017
• 脳内ニコチン受容体とアルツハイマー病 「ニューロン−グリア相互作用を介した神経保護・再生におけるニコチン受容体の役割」2016
• アルツハイマー病治療薬によるタウリン酸化抑制と新規神経保護作用機序の解析2013

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