Nagahama Institute of Bio-Science and Technology · Faculty of Pharmaceutical Sciences · 客員教授

Research fields薬系化学、創薬科学

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• Adachi M, Ohhara T, Kurihara K, Tamada T, Honjo E, Okazaki N, Arai S, Shoyama Y, Kimura K, Matsumura H, Sugiyama S, Adachi H, Takano K, Mori Y, Hidaka K, Kimura T, Hayashi Y, Kiso Y, Kuroki R: Structure of HIV-1 protease in complex with potent inhibitor KNI-272 determined by high resolution X-ray an2012
• Kiso Y, Taniguchi A, Sohma Y: Click peptides: design and applications. Wiley Encyclopedia of Chemical Biology, (ed. Tadhg P. Begley), Vol. 1, 379-383 (2009).2009
• Taniguchi A, Sohma Y, Hirayama Y, Mukai H, Kimura K, Hayashi Y, Matsuzaki K, Kiso Y: "Click peptide": pH-triggered in situ production and aggregation of monomer Aβ1-42. ChemBioChem, 10, 710-715 (2009) spotlighted in Angew. Chem. Int. Ed. 48, 2444 (2009).2009
• Nezami A, Kimura T, Hidaka K, Kiso A, Liu J, Kiso Y, Goldberg D E, Freire E: High affinity inhibition of a family of Plasmodium falciparum proteases by a designed adaptive inhibitor. Biochemistry, 42, 8459-8464 (2003) highlighted in Science, 301, 143 (2003).2003

• Design and Medicinal Chemistry Study of anti-incurable disease drugs
• 分子認識に基づく難病治療薬のデザインと医薬化学研究
• Molecule-based Medicinal Science Frontier Overcoming Difficult Diseases
• 難病克服をめざした分子基盤創薬科学の開拓

• Official profile