Nagasaki University · Faculty of Fisheries / Graduate School of Science and Technology

Research keywordsorganic synthesis・heterocyclic chemistry・topoisomerase I inhibitors・anticancer agents・pyridine functionalization・nitrile oxide cycloaddition・palladium catalysis・marine alkaloid synthesis

This is a public-data preview. Personalized fit, contact angles, and saved workflows require sign-in.

• Design, synthesis, and biological evaluation of novel benzo[6,7]indolo[3,4-c]isoquinolines as anticancer agents with topoisomerase I inhibition Kie Sakai,Taisei Soshima,Yuki Hirose,Fumito Ishibashi,Shotaro Hirao Bioorganic and Medicinal Chemistry Letters 104巻 2024年05月15日2024
• Synthesis of Unsymmetrical Ketones Using Chelation-Controlled Sequential Substitution of N-Triazinylamide/Weinreb Amide by Organometallic Reagents Shotaro Hirao,Rumi Saeki,Toru Takahashi,Kento Iwai,Nagatoshi Nishiwaki,Yasushi Ohga ACS Omega 7巻51号48476頁-48483頁 2022年12月2022
• Concise synthesis and in vitro anticancer activity of benzo[g][1]benzopyrano[4,3-b]indol-6(13H)-ones (BBPIs), topoisomerase I inhibitors based on the marine alkaloid lamellarin Fumito Ishibashi,Tsutomu Fukuda,Shijiao Zha,Aya Hashirano,Shotaro Hirao,Masatomo Iwao Bioscience, Biotechnology, and Biochemistry 85巻1号181頁-191頁 2021年01月2021
• Long-time relaxation of stress-induced birefringence of microcrystalline alkali halide crystals Hiroki Ueno,Ryoga Arakane,Yoshihisa Matsumoto,Tomoki Tsumura,Akihito Kitazaki,Toru Takahashi,Shotaro Hirao,Yasushi Ohga,Takunori Harada Molecules 23巻4号1頁-9頁 2018年03月2018

• トリアジン環によるC－N結合活性化を鍵とする低毒性な求電子的シアノ化反応の開発 日本学術振興会 科学研究費助成事業 2024年04月01日 - 2027年03月31日2024

• Official profile