Nagoya University · Faculty of Science / Graduate School of Science

Research keywordscircular mRNA・mRNA vaccines・mRNA delivery・CRISPR-Cas3 editing・human 5 prime UTR・lipid nanoparticles・type I interferon・DNA autoligation

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• CRISPR-Cas3-based editing for targeted deletions in a mouse model of transthyretin amyloidosis2026 · NATURE BIOTECHNOLOGY 2026年1月
• Covalently or non-covalently attached m7G cap enhances protein production from circular mRNA2026 · NATURE BIOTECHNOLOGY 44 巻 ( 1 ) 頁： 46 - 47 2026年1月
• Position-specific ORF nucleoside-ribose modifications enabled by complete chemical synthesis enhance mRNA stability and translation2025 · NATURE COMMUNICATIONS 16 巻 ( 1 ) 頁： 9995 2025年11月
• In vivo demonstration of enhanced mRNA delivery by cyclic disulfide-containing lipid nanoparticles for facilitating endosomal escape2025 · RSC MEDICINAL CHEMISTRY 16 巻 ( 9 ) 頁： 4122 - 4137 2025年9月

• 真核系における環状RNA翻訳反応の機構解析2018 · 研究課題/研究課題番号： 18K14357 2018年4月 - 2021年3月

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