Nara Medical University · Biochemistry · 特任助教

Research keywordsubiquitin ligases・targeted protein degradation・RNF183 signaling・lysosomal degradation・hypertonic stress response・ATP-binding cassette transporters・endoplasmic reticulum stress・mRNA vaccine secretion

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• Evaluating Signal Peptide Efficiency for Extracellular Protein Secretion for mRNA Vaccine Design2025 · Biological and Pharmaceutical Bulletin
• Development of a Versatile System for Evaluating the Target Protein Degradation Activity of Novel Ubiquitin Ligases Utilizing Existing PROTACs2025 · Biochemical and Biophysical Research Communications
• p53-independent tumor suppression by cell-cycle arrest via CREB/ATF transcription factor OASIS2023 · Cell Reports
• Production of BBF2H7‐derived small peptide fragments via endoplasmic reticulum stress‐dependent regulated intramembrane proteolysis2020 · The FASEB Journal

• 健康寿命の充実および延長を目指した、リソソームストレス応答の分子基盤の解明2026
• 神経・筋疾患の発症機序の理解を目指したリソソームストレス応答分子機構の解明2025
• ACE2のユビキチン化を介したコロナウイルス感染機構の解明と創薬への挑戦2023 · 科学研究費助成事業
• ユビキチン化を介したコロナウイルスの感染機構解明および創薬スクリーニング系の確立2022

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