Yokohama University of Pharmacy · Department of Health Pharmacy · 助教

Research keywords●ヒトiPS細胞由来脳オルガノイドを用いた医薬品/食品の機能性評価法の構築・●中枢疾患における脳ペリサイト-グリア細胞機能異常の解明・●認知症を予防する食品成分の探索・●概日リズム攪乱による血液脳関門機能異常の解明

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• 1. Yoshio Goshima , Haruko Nakamura, Motokazu Koga, Junka Koyama, Yayoi Kimura, Maya N Vasishth, Evan Y Snyder, Masashi Asai, Kenta Sakai , Daiki Masukawa 「Disruption of the l-DOPA Receptor Gpr143/OA1-Gene in Mice Creates a Unique Mixed Psychosis-Like Phenotype」 Neuropsychopharmacology reports 46(1) e70080 2026.2026
• 2. Kenta Sakai , Fuyuko Takata, Takuro Iwao, Miho Yasunaga, Gaku Yamanaka, Yasufumi Kataoka, Shinya Dohgu. 「Brain pericytes upregulate glutamate uptake by astrocytes in vitro through sodium-dependent transporter」 IBRO Neuroscience Reports 19 54-61 2025.2025
• 3. Tsunehiko Hongen, Kenta Sakai , Tomohiro Ito, Xian-Yang Qin, Hideko Sone 「Human-Induced Pluripotent Stem Cell-Derived Neural Organoids as a Novel In Vitro Platform for Developmental Neurotoxicity Assessment」 International Journal of Molecular Sciences 25(23) 12523 2024.2024
• 4. Lihong Cheng, Caiyue Shi, Saya Nakamura, Nana Esaki, Yuka Ichiba, Mitsuru Tanaka, Kenta Sakai , Toshiro Matsui. 「Adiponectin-Receptor Agonistic Dipeptide Tyr–Pro Stimulates the Acetylcholine Nervous System in NE-4C Cells」 Journal of Agricultural and Food Chemistry, 72, 13, 7121–7129, 2024.2024

• 非神経細胞系の制御による新たな認知症予防食科学戦略の構築
• ヒトiPS細胞由来脳オルガノイドを用いた食品成分の機能性ならびに安全性評価

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