Yokohama University of Pharmacy · Department of Pharmaceutical Sciences · 教授

Research keywords●生体内酸化還元関連タンパク質の転写調節機構の解明・●好熱性古細菌の環境適応遺伝子群の探索とそれらの転写制御機構の解明・●食道癌細胞に対するファージ単鎖(scFv)モノクローナル抗体の作製・Specificity・Fur・Binding・Oxidative・Stress

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• 2. Specificity of Fur Binding to the Oxidative Stress Response Gene Promoter in the Facultative Anaerobic Archaeon Thermoplasma volcanium. Minoshima H, Ikeda Y, Fujii M, Satoh M, Ishikawa T, Kawashima-Ohya Y, Tomobe K, Itoh Y, Omata Y, Kawashima T . Biol. Pharm. Bull. 37(3) 481-485, 2014.2014
• 1. Apoptosis occurs during early development of the bursa of Fabricius in chicken embryos. Makino K, Omachi R, Suzuki H, Tomobe K, Kawashima T , Nakajima T.,and Kawashima-Ohya Y. Biol. Pharm. Bull. 2014;37(12):1982-5.2014
• 3. Age-related changes of forkhead transcription factor FOXO1 in the liver of senescence-accelerated mouse SAMP8. Tomobe K, Shinozuka T, Kawashima T , Kawashima-Ohya Y, Nomura Y. Arch Gerontol Geriatr. 2013 Nov-Dec;57(3):417-422.2013
• 4. Transcriptional factor Fur from Thermoplasma volcanium binds its own promoter DNA in a divalent cation-dependent manner. Y. Ikeda, H. Minoshima, M. Satoh, T. Ishikawa, Y. Kawashima-Ohya, K. Tomobe, Y. Omata and T. Kawashima , J. Gen. Appl. Microbiol., 58, 465-473 (2012).2012

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