Yokohama University of Pharmacy · Department of Kampo Pharmacy · 教授

Research keywordsプロテオミクス・分離科学・天然物化学・質量分析・バイオマーカー

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• 2. Cancer cell immunity-related protein co-expression networks are associated with early-stage solid-predominant lung adenocarcinoma. Toshihide Nishimura, Ákos Végvári, Haruhiko Nakamura, Kiyonaga Fujii , Hiroki Sakai, Saeko Naruki, Naoki Furuya, Hisashi Saji Frontiers in oncology 14 1273780-1273780 2024年2024
• 1. Identifying simultaneous inhibition of riboflavin metabolism and MEK as a novel therapeutic strategy for pancreatic cancer Takako Ooshio, Yusuke Satoh, Hui Jiang, Tongwei Liu, Kiyonaga Fujii , Takamasa Ishikawa, Kaori Igarashi, Kaori Saitoh, Keiko Kato, Tetsuo Mashima … bioRxiv 2024年10月26日2024
• 3. Dimethylglycine, a Methionine Metabolite, Participates in the Suppressive Effect of Methionine on 1-Fluoro-2,4-dinitrobenzene-Induced Dermatitis. Takayuki Koga, Kie Inoue, Fuka Hirayama, Makoto Hiromura, Kiyonaga Fujii , Yuji Ishii, Masayo Hirao-Suzuki, Shuso Takeda, Akihisa Toda, Fumio Soeda Biological & pharmaceutical bulletin 46(7) 946-954 2023年7月1日2023
• 4. Perfluorooctanoic acid (PFOA) as a stimulator of estrogen receptor-negative breast cancer MDA-MB-231 cell aggressiveness: Evidence for involvement of fatty acid 2-hydroxylase (FA2H) in the stimulated cell migration Genki Sakai, Masayo Hirao-Suzuki, Takayuki Koga, Takananobu Kobayashi, Jun Kamishikiryo, Michitaka Tanaka, Kiyonaga Fujii , Masufumi Takiguchi, Narumi Sugihara, Akihisa Toda … Journal of Toxicological Sciences 47(4) 159-168 2022年2022

• 肝上皮系細胞の分化を規定するマスタースイッチの探索
• 鉄過剰投与による肝細胞特異的傷害―胆管上皮細胞・肝幹細胞分離への応用
• 全自動プロテオーム解析システムの構築と臨床検査診断への応用
• 膵臓がんの頑健性の分子基盤の解明とその破壊による新規治療法の確立

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