Nihon University · Department of Dentistry / Faculty of Dentistry · 助教

Research keywordsepithelial-mesenchymal plasticity・oral squamous cell carcinoma・Porphyromonas gingivalis・amino acid transporters・xCT-targeted therapy・drug repurposing・KRAS gastric cancer・monoclonal antibodies

Research fieldsTumor biology

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• 治療抵抗性頭頸部扁平上皮癌を標的とした治療薬の同定2025 · 日本歯科医師会雑誌, 2025年07月
• CD44v, S1PR1, HER3, MET and cancer-associated amino acid transporters are promising targets for the pancreatic cancers characterized using mAb.2025 · FEBS open bio, 2025年01月
• Mipep deficiency in adipocytes impairs mitochondrial protein maturation and leads to systemic inflammation and metabolic dysfunctions.2025 · Scientific reports, 2025年04月
• Drug Repurposing Screen Identifies Pimozide as a ROS-Inducing Therapy With Anti-Tumor Efficacy in HNSCC PDX Models.2025 · Cancer science, 2025年11月

• J鎖依存的に腸管粘膜固有層で分化する分泌型IgA産生細胞の起源ならびに機能の解明2024
• 歯周病発症機序のパラダイムシフトへの挑戦 ーヒト化マウスでのウイルス関与の立証 ー2024
• PDXモデルを用いた局所進行・再発転移口腔癌に対する新たな治療戦略の考案2023
• Actionable遺伝子変異に基づく新たな口腔扁平上皮癌治療戦略の開発2022

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