Nihon Pharmaceutical University · 薬学部 · 教授

Research keywordsSynthetic Organic Chemistry・有機合成化学・ヌクレオシド類似体・抗ウイルス活性・立体選択的合成・DNA損傷修復

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• Stereoselective synthesis of novel 4′-methylsulfanyl-pyrimidine ribonucleosides by means of nucleophilic substitution of the 4′-benzoyloxy leaving group2025 · Tetrahedron
• Synthesis of novel entecavir analogues having 4′-cyano-6′′-fluoromethylenecyclopentene skeletons as an aglycone moiety as highly potent and long-acting anti-hepatitis B virus agent2023 · RSC Advances
• Regio- and Stereoselective Synthesis of 2′-Deoxy-4′-thioguanine Nucleosides: Evaluation of Anti-Hepatitis B Virus Activity and Cytotoxicity Leading to Improved Selectivity Index by 4′-C-Cyanation2023 · Synlett
• 4-Thiofuranoid Glycal: Versatile Glycosyl Donor for the Selective Synthesis of β-anomer of 4'-thionucleoside and its Biological Activities.2022 · Current medicinal chemistry

• オキセタノイドグリカールを利用する分岐糖型オキセタノシンの合成とその生物活性2012 · 科学研究費助成事業
• DNAの損傷と修復の生物有機化学的研究2010
• ヌクレオシド系抗生物質の全合成研究2010
• Chemical Synthesis and Biological Activity of Thio Sugar Derivatives2010

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