Hoshi University · Division of Pharmacology and Clinical Pharmacy

Research keywordspain neuroscience・cancer progression・opioid pharmacology・cancer cachexia・hypothalamic microglia・stress neurons・exercise-induced hypoalgesia・dopamine receptors

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• Pain signaling via sensory neurons drives breast cancer progression through neuropeptide release and κ-opioid counter-regulation2026 · Pharmacological Research
• Emesis and Constipation Induced by Methadone and the Active Metabolite of Tramadol (M1) in Animals.2025 · Journal of applied toxicology : JAT
• Peripheral-central network analysis of cancer cachexia status accompanied by the polarization of hypothalamic microglia with low expression of inhibitory immune checkpoint receptors.2024 · Molecular brain
• Elucidation of the mechanisms of exercise-induced hypoalgesia and pain prolongation due to physical stress and the restriction of movement.2023 · Neurobiology of pain (Cambridge, Mass.)

• Sigma-1受容体シャペロンの細胞保護作用を利用したがん細胞脆弱化手法の探索2024 · 科学研究費助成事業
• D2-受容体含有中型有棘神経細胞選択的調節によるドパミン関連疾患の病態の機序解明2018 · 科学研究費助成事業
• 次世代の“包括的緩和医療”を支える最先端基礎／臨床融合型研究の基盤形成2016
• シグマ受容体シャペロンによる細胞保護作用およびμ-受容体機能調節の機序解明2015 · 基盤研究(C)

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