Obihiro University of Agriculture and Veterinary Medicine · Center for Global Agromedicine Research · 教授

Research keywords畜産・核内受容体・感受性・獣医学

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• Sex differences in the accumulation of chlorinated dioxins in the cormorant (Phalacrocorax carbo): Implication of hepatic sequestration in the maternal transfer
• Protective effect of prostacyclin against pre-cardiac edema caused by 2,3,7,8-tetrachlorodibenzo-p-dioxin and a thromboxane receptor agonist in developing zebrafish.
• Ahr2-dependence of PCB126 effects on the swim bladder in relation to expression of CYP1 and cox-2 genes in developing zebrafish.
• The evolution of UDP-glycosyl/glucuronosyltransferase 1E (UGT1E) genes in bird lineages is linked to feeding habits but UGT2 genes is not.

• 化学物質曝露により活性化される魚類の核内受容体とその標的遺伝子の探索
• 魚類のダイオキシン動態及び毒性におけるチトクロームP450の新たな役割
• 魚類の核内受容体PXRシグナル経路の撹乱に関わる新規分子機構とその毒性学的意義
• 多元的オミックス解析による化学物質ー細胞内受容体シグナル伝達撹乱の種差の解明

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