Okayama University of Science · Faculty of Veterinary Medicine · 准教授

Research keywords分子間パスウェイ・遺伝子発現解析・肝毒性・オミクス解析・遺伝子発現・腎臓・肝臓・発がん

Research fieldsGenome biology・Molecular biology・毒性学

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• Developmental cuprizone exposure impairs oligodendrocyte lineages differentially in cortical and white matter tissues and suppresses glutamatergic neurogenesis signals and synaptic plasticity in the hippocampal dentate gyrus of rats
• Differences in gene expression profiles in liver caused by different types of anesthesia: cases of CO2-O-2 and isoflurane
• Molecular Profiling of Human Induced Pluripotent Stem Cell Derived Cells and Their Application for the Drug Safety Study
• Applicability of a gene expression based prediction method to SD and Wistar rats: an example of CARCINOscreen®.

• 遺伝子発現解析技術を用いた発がん性予測手法の開発
• 化学物質により誘発される脂肪変性の毒性パスウェイ解析
• ラットへの28日間反復投与及びマイクロアレイによる網羅的な遺伝子発現量解析
• 培養細胞への化学物質暴露で生じる細胞毒性とアポトーシス誘導との関係性

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