Okayama University of Science · Faculty of Veterinary Medicine · 助教

Research keywords高血圧・Eukaryotic elongation factor 2 kinase・リンパ管・獣医薬理学・糖尿病・血管

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• Visceral adipose tissue-derived serine protease inhibitor prevents the development of monocrotaline-induced pulmonary arterial hypertension in rats.
• Age-dependent increase in activity of eukaryotic elongation factor 2 kinase in mesenteric arteries from spontaneously hypertensive rats
• Adipocytokine, progranulin, augments acetylcholine-induced nitric oxide-mediated relaxation through the increases of cGMP production in rat isolated mesenteric artery
• Autocrine role of senescent cardiac fibroblasts-derived extracellular vesicles.

• eEF2Kをターゲットとした新たな循環器疾患治療薬の探索
• 真核生物伸長因子2キナーゼがリンパ管機能障害を介して糖尿病病態に及ぼす影響の解明
• 中枢と腎臓における真核生物伸長因子2キナーゼの役割解明と高血圧症治療薬の探索

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