Okayama University · Institute of Medicine, Dentistry and Pharmaceutical Sciences · 教授

Research keywords自己免疫性関節炎・炎症性Tヘルパー細胞

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• Graded Attenuation of TCR Signaling Elicits Distinct Autoimmune Diseases by Altering Thymic T Cell Selection and Regulatory T Cell Function
• SKG mice, a monogenic model of autoimmune arthritis due to altered signal transduction in T cells.
• Stress-induced glucocorticoids enhance acute inflammation by promoting the differentiation of Th17 cells.
• Control of immune responses by antigen-specific regulatory T cells expressing the folate receptor

• Th17細胞による粘膜免疫維持機構の解明
• 炎症性Th17細胞の制御機構と組織炎症の分子基盤
• GM-CSF産生Th細胞の分子制御メカニズム解明への挑戦
• 関節リウマチを中心とした自己免疫病の免疫学的基盤の解明と新規治療法・予防法の確立

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