Osaka Medical and Pharmaceutical University · Graduate School of Pharmaceutical Sciences / Department of Pharmacy / Faculty of Pharmaceutical Sciences · 教授

Research keywordsStructural analysis of bio-organic compounds・X-Ray crystallography・X線結晶構造・ペプチド化学・分子設計・生体関連物質の構造解析・Molecular design

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• Helical Template Peptides Containing Cyclic α,α-Disubstituted Amino Acids: Ring-Size Effects on Conformation and siRNA Delivery.2026 · The Journal of organic chemistry
• Evaluation of peptide secondary structure and intracellular uptake by introducing disubstituted amino acids into the amphipathic helical peptide C18AA2025 · Results in Chemistry
• Redox‐Responsive Side Chain Structural Changes in a Seven‐Membered Cyclic α,α‐Disubstituted α‐Amino Acid with a Disulfide Bond Enable Reversible Conformational Changes in Peptides2025 · ChemPlusChem / Wiley / 90 / 4
• Discovery of novel disulfide-containing PD-1/PD-L1 inhibitor with in vivo influenza therapeutic efficacy2025 · Scientific Reports / Springer Science and Business Media LLC / 15 / 1

• ジ置換アミノ酸の特徴を活かした膜透過性ペプチドの創製とDDSキャリアとしての応用2017
• βアミノ酸導入によるエラスチンフラグメントの医療基剤への応用2008
• 環状ジ置換アミノ酸配座固定ペプチドライブラリーによる免疫制御分子の探索2007
• ヘテロ分子間の相互作用形態-PNAの構造化学的性質と応用-1995

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