Osaka Medical and Pharmaceutical University · Graduate School of Pharmaceutical Sciences / Department of Pharmacy / Faculty of Pharmaceutical Sciences

Research keywords有機合成化学・計算化学・HDAC阻害剤・天然物化学・抗ウイルス活性・抗がん活性・神経保護・医薬品化学

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• Discovery of novel disulfide-containing PD-1/PD-L1 inhibitor with in vivo influenza therapeutic efficacy2025 · Scientific Reports / Springer Science and Business Media LLC / 15 / 1
• Experimental and DFT Studies of Intermolecular Interaction-Assisted Oxindole Cyclization Reaction of Di-t-butyl 2-Aminophenyl-2-methyl Malonate2025 · Chemical and Pharmaceutical Bulletin / Pharmaceutical Society of Japan / 73 / 1
• Isozyme-specific histone deacetylase 1/2 inhibitor K560 attenuates oxidative stress-induced retinal cell death.2023 · Neuroscience letters / 793
• [Isoform Selectivity of HDAC Inhibitors Has a Significant Effect on PD-L1 Expression in the Triple-negative Cancer Cell Line MDA-MB-231].2022 · Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan / 142 / 4

• ＴＯＲＣ及びＨＤＡＣ制御機構の解明と新規低分子化合物による神経疾患治療法の開発2012
• ERK-MAP キナーゼ経路の選択的遮断を基盤としたがん化学療法の開発2010
• 遺伝子導入・発現増強剤としての正電荷ヒストン脱アセチル化酵素阻害剤の開発2009
• DDSを指向したヒストン脱アセチル化酵素阻害剤の創生2007

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