Osaka Medical and Pharmaceutical University · Graduate School of Pharmaceutical Sciences / Department of Pharmacy / Faculty of Pharmaceutical Sciences · 准教授

Research keywordstau antibodies・tau aggregation・cytotoxic natural products・marine actinomycetes・depsidones・limonoids・crystallography・antimicrobial metabolites

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• Precise ligand-selective mechanism at the fab domain of a tau-recognizing antibody2025 · Journal of Structural Biology
• Botryorhodines K and L, two new cytotoxic depsidones from a fungus of the genus Arcopilus2023 · The Journal of Antibiotics / Springer Science and Business Media LLC / 76 / 11
• Marinoquinolones and Marinobactoic Acid: Antimicrobial and Cytotoxic ortho-Dialkylbenzene-Class Metabolites Produced by a Marine Obligate Gammaproteobacterium of the Genus Marinobacterium.2022 · Journal of natural products / 85 / 7
• Kumemicinones A-G, Cytotoxic Angucyclinones from a Deep Sea-Derived Actinomycete of the Genus Actinomadura2022 · JOURNAL OF NATURAL PRODUCTS / 85 / 4

• タウ重合に必須なCH-π相互作用阻害剤の開発:認知症治療薬開発の基盤研究2011
• 新規抗ガン剤開発のための翻訳開始因子4Eの機能制御物質の探索2010
• タウ蛋白質のタングル形成阻害剤の開発:認知症治療・予防薬開発のための基盤研究2008
• タウ蛋白質の自己凝集機構の解明:認知症治療薬開発のための基盤研究2005

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