Osaka University · Faculty of Pharmaceutical Sciences / Graduate School of Pharmaceutical Sciences

Research keywordsoligonucleotide chemistry・antisense oligonucleotides・ligand-oligonucleotide conjugates・bridged nucleic acids・solid-phase oligonucleotide synthesis・duplex formation・phosphonoacetate modification・DNA-encoded libraries・nuclease resistance・nucleobase modification

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• Amidation of Phosphonoacetate-Modified Oligonucleotides and Evaluation of the Properties of the Synthesized Oligonucleotides2026 · Organic Letters Vol. 28 No. 17 p. 5418-5423 2026年4月16日 研究論文（学術雑誌）
• Developing Methods for the Synthesis of Ligand-Oligonucleotide Conjugates for Drug Discovery Applications.2025 · Chemical & Pharmaceutical Bulletin Vol. 73 No. 9 p. 762-771 2025年9月 研究論文（学術雑誌）
• Antisense oligonucleotide targeting nicotinamide N-methyltransferase exhibits antitumor effects2025 · Molecular Therapy Nucleic Acids 2025年4月 研究論文（学術雑誌）
• Effects of acid-mediated deamination of cytidine and 5-methylcytidine on solid-phase synthesis of oligonucleotides2025 · Tetrahedron Vol. 185 2025年7月 研究論文（学術雑誌）

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