Kobe Pharmaceutical University · Faculty of Pharmaceutical Sciences · 講師

Research keywordsextracellular vesicles・probiotics・immunoadjuvants・drug delivery・bioorthogonal chemistry・innate immunity・kidney targeting・hydrogel functionalization

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• Extracellular vesicles from microalgae Pavlova in non-heated condition potently enhance innate immune response as a novel cell-derived immunostimulatory adjuvant.2026
• Functional Modification of Probiotic-Derived Extracellular Vesicles Based on Bioorthogonal Reaction for Immunotherapy: Hydrogelation and Immunoactivities2025 · YAKUGAKU ZASSHI
• Optimizing Prebiotic Saccharides in Culture Medium for the Bifidobacteria-Derived Extracellular Vesicles as Biomaterial Immunoadjuvant2025 · Biological and Pharmaceutical Bulletin
• Versatile functionalization of Bifidobacteria-derived extracellular vesicles using amino acid metabolic labeling and click chemistry for immunotherapy.2024

• 細胞外小胞を用いた腸内細菌叢制御DDSによるがん治療2026
• 多種ネオ抗原を搭載した善玉菌細胞外小胞による個別化がんワクチン療法の開発2026
• 腫瘍微小環境を制御する善玉菌由来膜小胞―免疫チェックポイント阻害抗体の創製と難治性がん治療への応用2024
• 細胞を基盤とした革新的がん指向型DDSの開発とその難治性がん治療への応用2024

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