Kobe Pharmaceutical University · Faculty of Pharmaceutical Sciences · 准教授

Research keywordsCOX 2 PET imaging・radiopharmaceutical development・alphaVbeta6 integrin targeting・photoimmunotherapy・activatable fluorescence imaging・macrophage molecular imaging・exosome tumor promotion・liposomal drug release control

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• Construction of nanostructured DNA harbouring phosphorodiamidate morpholino oligonucleotide for controlled tissue distribution in mice.
• Development of human serum albumin conjugated with near-infrared dye for photoacoustic tumor imaging.
• Synthesis of radioiodinated probes targeted toward matrix metalloproteinase-12.
• Detection of lipid radicals generated via cerebral ischemia/reperfusion injury using a radiolabeled nitroxide probe

• 活性酸素の分子種の動態を区別して追跡可能な放射性プローブの開発
• 近赤外光を用いる光音響法によるがんの生体分子イメージング法と治療法の開発
• スマートポリマーを基盤とするがんのラジオセラノスティクス薬剤の創製
• 外部刺激に応答するがん標的セラノスティックナノデバイスの開発

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