Kobe Pharmaceutical University · Faculty of Pharmaceutical Sciences · 講師

Research keywordsVitamin D・metabolism・identification of structure of metabolites・calcium・健康サポート・ロコモティブシンドローム・ビタミンＫ・ビタミンＤ・Vitamin K・体内動態

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• Sequential metabolism of 2,3,7-trichlorodibenzo-P-dioxin (2,3,7-triCDD) by cytochrome P450 and UDP-glucuronosyltransferase in human liver microsomes
• ビタミンK体内動態の解明を目指したMenadioneとその抱合体の定量法の確立
• [In vivo metabolism of vitamin K: in relation to the conversion of vitamin K1 to MK-4].
• Functional characterization of the vitamin K2 biosynthetic enzyme UBIAD1.

• Assay of Vitamin K in human plasma
• 牛乳および乳製品に含まれるビタミンＤ活性代謝物の定量と25-hydroxyvitamin D摂取の有用性に関する研究
• 癌細胞の分化とアポトーシスを構造選択的に制御するビタミンD誘導体の開発
• Biological activity of novel synthetic vitamin D analogs

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