Osaka University · Faculty of Pharmaceutical Sciences / Graduate School of Pharmaceutical Sciences

Research keywordsgamma-glutamylcysteine・glutathione metabolism・phytochelatin synthase・enzyme immobilization・biosensor development・metal ion complexation・angiotensin-converting enzyme inhibition・yeast surface engineering

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• Effective Repeated Production of γ-glutamylcysteine, Essential For Intracellular Glutathione Production, Using Cellulose-immobilized Phytochelatin Synthase-like Enzyme NsPCS2025 · Applied Biochemistry and Biotechnology 2025年1月21日 研究論文（学術雑誌）
• The Lower Toxicity and Wider Safety Range of Acidic Sophorolipid Compared to Surfactin and Rhamnolipid as Biosurfactants toward the HaCAT, THP-1, and RAW 264.72024 · BPB Reports Vol. 7 No. 2 p. 56-60 2024年3月 研究論文（学術雑誌）
• γ-Glutamylcysteine, a Glutathione Precursor, Exhibits Higher Thiol Reactivity for Complex Formation with Iron (III) Ions Compared to Glutathione2024 · BPB Reports Vol. 7 No. 6 p. 218-222 2024年10月 研究論文（学術雑誌）
• Gamma-Glutamylcysteine Production Using Phytochelatin Synthase-Like Enzyme Derived from Nostoc sp. Covalently Immobilized on a Cellulose Carrier2022 · Biological and Pharmaceutical Bulletin Vol. 45 No. 8 p. 1191-1197 2022年8月1日 研究論文（学術雑誌）

• γグルタミルシステインの正常な細胞機能や分化を維持する増殖因子としての解析・評価
• フィトケラチン合成酵素を用いた多様な重金属検出が可能な高感度バイオセンサーの開発

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