Juntendo University · Graduate School of Medicine / Faculty of Medicine · 特任教授

Research keywordsCD26/DPPIV・IL26・T細胞共刺激分子・ヒト免疫・ヒト化CD26抗体・悪性胸膜中皮腫・膠原病・自己免疫疾患

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• The CD70-CD27 interaction during the stimulation with dendritic cells promotes naive CD4+ T cells to develop into T cells producing a broad array of immunostimulatory cytokines in humans
• Cardiomyocyte-Specific Overexpression of HEXIM1 Prevents Right Ventricular Hypertrophy in Hypoxia-Induced Pulmonary Hypertension in Mice
• Optimal stimulation for CD70 induction on human monocyte-derived dendritic cells and the importance of CD70 in naive CD4+ T-cell differentiation
• Ligand-based gene expression profiling reveals novel roles of glucocorticoid receptor in cardiac metabolism

• β1インテグリン及びその関連分子の癌転移・浸潤及び癌病態における意義の解析
• アスベストばく露による悪性中皮腫の分子基盤に基づく新治療法の開発
• 悪性中皮腫の発生機構及び病態の解明
• CD29/VLAインテグリンの免疫制御機構とその臨床的意義の解析

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