Shinshu University · Department of Medicine / Faculty of Medicine · 教授

Research keywordsLOX 1 receptor biology・oxidized LDL・atherosclerosis・platelet activation・cardiomyocyte apoptosis・scavenger receptors

Research fieldsGeneral pharmacology・General internal medicine (including Psychosomatic medicine)・Clinical internal medicine・General medical chemistry・Medicine・Medicine, Dentistry, and Pharmacy・Basic medicine・Clinical surgery

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• Adiponectin forms a complex with atherogenic LDL and inhibits its downstream effects.
• LOX-1 mediates vascular lipid retention under hypertensive state.
• Expression of lectin-like oxidized low-density lipoprotein receptor-1 in allografted hearts.
• Increased expression of CD38 on endothelial cells in SARS-CoV-2 infection in cynomolgus macaque.

• エンドセリン変換酵素によるエンドセリン産生制御
• 骨格筋の新機能としての老廃物除去機能を解明する
• レクチン様酸化LDL受容体の機能と病態生理的役割
• エンドセリン変換酵素によるエンドセリン産生制御

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