Tokyo University of Science · Research Faculty of Liberal Arts Education · 准教授

Research keywordsgold nanoparticles・DNA cleavage assay・colorimetric biosensing・surface plasmon resonance・SNP genotyping・nucleic acid delivery

Research fieldsBiomedical engineering・Chemistry・Science and Engineering・Biomedical engineering/Biomaterial science and engineering・Chemistry related to living body・Integrated Disciplines・Applied Chemistry・Complex systems

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• Acid-triggered nucleic acid release from gold nanoparticles via Schiff base linkages: In vitro validation of endosomal escape and gene silencing
• Microcalorimetric Study of the Temperature-induced Phase Separation in Aqueous Solutions of Poly(2-isopropyl-2-oxazolines)
• Versatile Synthesis of End-Functionalized Thermosensitive Poly(2-isopropyl-2-oxazolines)
• Connecting Nanoparticles with Different Colloidal Stability by DNA for Programmed Anisotropic Self-Assembly

• 新規遺伝子ベクターへの展開を目指したブロック共重合体ミセルの構造設計と物性評価
• 核酸医薬をDNA密生層としたナノ構造体の作製とキャリアフリーDDSの創製
• DNAソフト界面の特性を活かしたバイオマテリアルの創製
• 核酸塩基を薬剤修飾素子としたsiRNA密生型キャリアフリーナノDDS製剤の創製

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