Kumamoto University · Research Division of Life Sciences · 教授

Research keywords大腸癌・胃癌・膵癌・肝細胞癌・胆道癌・食道癌・腫瘍微小環境・免疫チェックポイント阻害薬・ctDNA・gastric adenocarcinoma proximal polyposis

Research fieldsGeneral surgery・Digestive surgery・Medicine, Dentistry, and Pharmacy・Clinical surgery・Biological Sciences

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• Frizzled-1 amplification promotes fibrosis in the gastric tumor microenvironment through the activation of fibroblasts via the SLIT2/ROBO1 axis.2026 · Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association
• Context-Dependent Roles of ANGPTL2-Mediated Inflammaging in Tissue Homeostasis, Pathological Tissue Remodeling, and Longevity.2026 · Aging cell
• A case of dramatic response to pembrolizumab monotherapy in dMMR unresectable colorectal cancer diagnosed following abdominal hemorrhage due to segmental arterial mediolysis.2026 · Clinical journal of gastroenterology
• Relationship between nutritional indicators and clinicopathological factors, including immune cell densities in the tumor microenvironment, in patients with colorectal cancer.2026 · Medical molecular morphology

• 遺伝性胃癌臨床検体を用いた上部胃癌発癌メカニズムの解明と革新的治療法の確立2024 · 科学研究費助成事業
• 革新的治療法開発を目指した食道胃接合部腺癌の網羅的ゲノム解析2021 · 科学研究費助成事業
• FusobacteriumによるNOD/NF-κBを介した食道癌進展機序の解明2021 · 科学研究費助成事業
• 胃癌腹膜播種における腫瘍不均一性および腫瘍微小環境を標的とした革新的治療法の開発2020 · 科学研究費助成事業 基盤研究(C)

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