Komazawa University · Faculty of Medical and Health Sciences · 准教授

Research keywordsglycobiosensors・quartz crystal microbalance・localized surface plasmon resonance・lectin sensing・molecularly imprinted hydrogels・protein affinity evaluation・AC microelectrophoresis・metalloglycoclusters

Research fieldsBiomedical engineering・Chemical biology・Clinical internal medicine・Medicine, Dentistry, and Pharmacy・Biomedical engineering/Biological material science・Radiation science・Living organism molecular science・Biomedical engineering/Biomaterial science and engineering

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• Evaluation of Interaction Forces between Profilin and Designed Peptide Probes by Atomic Force Microscopy (Langmuir)
• Direct Measurement of Interaction Forces between a Platinum Dichloride Complex and DNA Molecules (J. Biological Physics)
• Switchable Binding Affinity of Mannose Tethered to Collagen Peptide by Temperature-Dependent Triple-Helix Formation (Bioconjugate Chem.)
• Enhanced Binding Specificity between Lectin and Ruthenium Metalloglycocluster bearing Galactose

• 酵素反応を利用した蛍光金属錯体型糖鎖プローブ分子の汎用化技術の開発
• 生体膜融合特性をもつ蛍光金属錯体型糖鎖の創製と癌細胞ターゲッティングへの展開
• ハイブリッドMRI造影剤創製と動物実験による他の造影剤との性能の基礎的比較検討
• 温度応答性を付与した癌細胞造影剤の新規構造モジュールの構築

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