Doshisha Women's College of Liberal Arts · Faculty of Pharmaceutical Sciences · 教授

Research keywordsCYP2C9・薬物代謝・重水素化医薬品・HLA-B*35:01・HLA-B*58:01・抗生物質品質評価

Research fieldsClinical internal medicine・Medicine, Dentistry, and Pharmacy・Medical pharmacy・Boundary medicine・Applied pharmacology・Physical pharmacy・Biological Sciences・Biological Sciences

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• Quality Evaluation of Gentamicin Sulfate Reference Standards in Japanese Pharmacopoeia Using Hydrophilic Interaction Chromatography Combined With Tandem Mass Spectrometry. Journal of AOAC International 107 (2),234-241 (共著) 2024/032024 · 著書・論文歴
• Structural and biophysical analysis of cytochrome P450 2C9*14 and *27 variants in complex with losartan. Journal of inorganic biochemistry 258,112622 (共著) 2024/092024 · 著書・論文歴
• Validation of a genotyping technique for a surrogate marker of HLA-B∗58:01 for allopurinol-induced Stevens-Johnson syndrome and toxic epidermal necrolysis in the Japanese population. Drug metabolism and pharmacokinetics 49,100495 (共著) 2023/042023 · 著書・論文歴
• Significant association between HLA-B*35:01 and onset of drug-induced liver injury caused by Kampo medicines in Japanese patients. Hepatology research : the official journal of the Japan Society of Hepatology 53 (5),440-449 (共著) 2023/052023 · 著書・論文歴

• 抗生物質の品質評価手法の開発および標準化に関する研究 企業からの受託研究科研費・外部資金による研究
• CYP2U1の脱オーファン化にむけた酵素活性、及び立体構造の解明に関する研究 基盤研究（Ｃ）科研費・外部資金による研究
• 抗生物質の品質評価手法の標準化に関する研究 企業からの受託研究科研費・外部資金による研究
• 医薬品の有効性・安全性に係るバイオマーカーの探索研究研究課題

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