Kyoto University · Faculty of Medicine / Graduate School of Medicine · 教授

Research keywords病原性・細菌学・cell biology・ゲノム・創薬・感染症・抗体・細胞生物学

Research fieldsMorphological basic dentistry・Orthodontic/Pediatric dentistry・Bacteriology (including Mycology)・Periodontal dentistry・Dentistry・Animal life science・Medicine・Medicine, Dentistry, and Pharmacy

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• Genome sequence of an M3 strain of Streptococcus pyogenes reveals a large-scale genomic rearrangement in invasive strains and new insights into phage evolutionGENOME RESEARCH,
• Comparative genomic analyses of Streptococcus mutans provide insights into chromosomal shuffling and species-specific contentBMC GENOMICS,
• Correction: Significance of a histone-like protein with its native structure for the diagnosis of asymptomatic tuberculosis.PloS one,
• Inhibitory effects of protamines on proteolytic and adhesive activities of Porphyromonas gingivalisINFECTION AND IMMUNITY,

• 分子間相互作用阻害に基づく菌種特異的な増殖阻害剤の開発
• 歯周病原性細菌の宿主細胞内侵入と歯周組織破壊機構の分子生物学的解析
• 口腔内細菌の定着・付着に関する研究
• レンサ球菌属のCRISPRスペーサー配列解析による新規流行株予測法の確立

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