Hokkaido University · Faculty of Medicine / Graduate School of Medicine / Medical Research Institute · 教授

Research keywordsTRIMタンパク質・ユビキチンリガーゼ・Molecular・ligase・タンパク質分解・ユビキチン・プロテアソーム・Ubiquitin

Research fieldsGeneral medical chemistry・Experimental pathology・Functional biochemistry・Pathological medical chemistry・Neurology・Immunology・内科・Clinical internal medicine

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• Bacterial extracellular vesicle ssRNA prevents colorectal cancer progression via Piezo1.2025 · Cell reports, 45, 1, 116737, 116737, 2025年12月17日,
• PPM1D is directly degraded by proteasomes in a ubiquitination-independent manner through its carboxyl-terminal region.2025 · Journal of biomedical science, 32, 1, 88, 88, 2025年09月11日,
• Development of a Myogenin minimal promoter-based system for visualizing the degree of myogenic differentiation2024 · Biochemical and Biophysical Research Communications, 2024年11月,
• Neuroimmune modulation by tryptophan derivatives in neurological and inflammatory disorders.2024 · European journal of cell biology, 103, 2, 151418, 151418, 2024年05月08日,

• CD4サイレンシングの分子機構とリンパ球分化過程におけるRunxの役割の解明
• プロテオーム解析による頭頸部癌診断・治療の新しい展開
• TRIM型ユビキチンリガーゼの物性と動作原理の解析
• 性ホルモン受容体のユヒキチン化介在性分解による癌細胞増殖制御機構

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