Tokyo University of Science · Graduate School of Advanced Interdisciplinary Science and Technology / Faculty of Advanced Interdisciplinary Science and Technology · 教授

Research keywordsクロマチン・エピジェネティクス・がん・老化・細胞周期・染色体・創薬・テロメア

Research fieldsBasic biology・Biology・Biological Sciences・Biological Sciences・Oncology・Tumor biology・Genetics/Genome dynamics

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• Extrinsic induction of apoptosis and tumor suppression via the p53–Reprimo–Hippo–YAP/TAZ–p73 pathway2025 · PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
• Cytochrome P450 2J2 is required for the natural compound austocystin D to elicit cancer cell toxicity2024 · CANCER SCIENCE
• DHX36 maintains genomic integrity by unwinding G-quadruplexes2023 · GENES TO CELLS
• Deoxygenation of tertiary and secondary alcohols with sodium borohydride, trimethylsilyl chloride, and potassium iodide in acetonitrile.2021 · TETRAHEDRON LETTERS

• 天然化合物AusDの生物活性に高い感受性を示すがん細胞の分子遺伝学的特徴の解明
• SETドメインタンパク質によるタンパク質メチル化の生理機能
• ATRXが関与するゲノム維持機能の分子ネットワークの解明と疾患理解への応用
• 細胞老化と癌抑制を誘導する遺伝子発現機構

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