Institute of Science Tokyo · Institute for Advanced Studies · 教授

Research keywordsロボット科学・分子生物学・Molecular Biology・Cell Biology

Research fieldsNeurochemistry/Neuropharmacology・Experimental pathology・Functional biochemistry・Neuroscience・Cell biology・Oncology・Genome science・System genome science

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• Cardiomyocyte-specific Fbxl5 deficiency promotes iron overload-driven hypercontractility and late-onset pathological hypertrophy in mice2026
• Protection of stromal cell-derived factor 2 by heat shock protein 72 prevents oxaliplatin-induced cell death in oxaliplatin-resistant human gastric cancer cells
• The promise of targeted proteomics for quantitative network biology
• Activation of cyclin-dependent kinase 2 (Cdk2) in growth-stimulated rat astrocytes - Geranylgeranylated Rho small GTPase(s) are essential for the induction of cyclin E gene expression

• プロテアソームへのユビキチン化基質のターゲッテング機構の解析
• 成体神経幹細胞の発生起源とその制御機構
• 異常蛋白質の特異的分解機構を応用した神経変性疾患に対する遺伝子治療法の開発
• 神経機能調節におけるRabファミリーの制御機構

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