Kyoto University · Faculty of Agriculture / Graduate School of Agriculture · 准教授

Research keywordsアミロイド蛋白質・ケミカルバイオロジー・スーパーカルコゲノイド・メタアグリゲート・核酸アプタマー・機能性食品分子・Development・platinum

Research fieldsBiological Sciences・Living organism molecular science・Biomolecular chemistry・Bioorganic chemistry・Bioproduction chemistry/Bioorganic chemistry・Integrated Disciplines・Complex systems・Agriculture

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• Modeling Alzheimer’s disease with iPSCs reveals stress phenotypes associated with intracellular Aβ and differential drug responsiveness.2013 · Cell Stem Cell 12 (4), 487-496 (2013).,
• Development of a platinum complex as an anti-amyloid agent for the therapy of Alzheimer’s disease.2013 · Angew. Chem. Int. Ed. 52 (12), 3374-3378 (2013).,
• Early accumulation of intracellular finrillar oligomers and late congophilic amyloid angiopathy in mice overexpressing the Osaka intra-Aβ APP mutation.2012 · Transl. Psychiatry 2012, 2, e183 (2012).,
• ComX pheromone precursor contains no consensus sequence necessary for tryptophan prenylation.2012 · Biosci. Biotechnol. Biochem. 76 (8), 1492-1496 (2012).,

• 腸内細菌生産天然物コリバクチンによる大腸がん発症機構に関する有機化学的研究
• βアミロイドの病的コンホメーションを標的としたアルツハイマー病治療薬の設計
• βアミロイドの凝集機構に関する有機化学的研究
• アミロイドβオリゴマーの形成阻害機構に関する構造有機化学的研究

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