The Jikei University School of Medicine · Graduate School of Medicine / Faculty of Medicine · 教授

Research keywordsamino acid transporters・membrane transport proteins・LAT1・cystinuria・urate transport・mTOR signaling・tumor angiogenesis・ER-Golgi trafficking・bile acid transport・hepatitis B virus entry

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• IDENTIFICATION OF A HYPOURICEMIA PATIENT WITH SLC2A9 R380W, A PATHOGENIC MUTATION FOR RENAL HYPOURICEMIA TYPE 2
• A Novel Transporter of SLC22 Family Specifically Transports Prostaglandins and Co-localizes with 15-Hydroxyprostaglandin Dehydrogenase in Renal Proximal Tubules
• Extracellular Vesicle Cargo from Lipofibroblasts Mitigates COPD by Alveolar Type II Cell Restoration.
• Transport of 3-fluoro-L-α-methyl-tyrosine by tumor-upregulated L-type amino acid transporter 1: a cause of the tumor uptake in PET.

• 先端遺伝子工学を駆使した変動性難聴モデル動物の確立とその応用
• 有機溶質トランスポートソーム:その構築と機能的意義
• 階層的アプローチによる膜輸送体の隠されている生理的基質の解明
• 新規リパーゼ様膜蛋白質による皮膚バリア機能形成機序の解明と制御薬物の探索

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