Tokyo University of Science · Institute of Biomedical Sciences · 准教授

Research fieldsImmunology・Medicine, Dentistry, and Pharmacy・Basic medicine・Biological Sciences・Society medicine・Hygiene and public health

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• Disulfiram Ophthalmic Solution Inhibited Macrophage Infiltration by Suppressing Macrophage Pseudopodia Formation in a Rat Corneal Alkali Burn Model2023 · International Journal of Molecular Sciences
• Inhibition of the chemokine signal regulator FROUNT by disulfiram ameliorates crescentic glomerulonephritis.2022 · KIDNEY INTERNATIONAL
• Disulfiram Produces Potent Anxiolytic-Like Effects Without Benzodiazepine Anxiolytics-Related Adverse Effects in Mice.2022 · Frontiers in Pharmacology
• Radiosynthesis of [thiocarbonyl-(11)C]disulfiram and its first PET study in mice.2020 · BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

• 肺移植後慢性拒絶におけるマクロファージの役割解明とFROUNT阻害による機能制御
• 機能性システインの化学修飾に基づく新規作用機序の炎症制御化合物の開発
• 重症COVID-19合併ARDS・マクロファージ活性化症候群の新規治療戦略の確立
• 疾患病態を反映するマクロファージの免疫形態学的指標の探索

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