Keio University · Faculty of Medicine / Graduate School of Medicine

Research keywordssmall cell lung cancer・lung adenocarcinoma・EGFR mutation・cell-free DNA epigenomics・Wnt dependency・immune checkpoint therapy・IGF-1 signaling・COX-2 signaling

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• Initial single-institutional experience with salvage surgery for stage IV non-small-cell lung cancer2025 · Interdisciplinary Cardiovascular and Thoracic Surgery 40
• An organoid library unveils subtype-specific IGF-1 dependency via a YAP–AP1 axis in human small cell lung cancer2025 · Nature Cancer 6
• Basal-shift transformation leads to EGFR therapy-resistance in human lung adenocarcinoma2025 · Nature Communications 16
• Celecoxib prevents malignant progression of smoking-induced lung tumors via suppression of the COX-2/PGE2 signaling pathway in mice2025 · Frontiers in Immunology 16

• 治療抵抗性肺癌オルガノイドライブラリーを用いた獲得耐性機構の本態解明2025 · -
• 酸素を用いた癌治療法の開発2024 · -
• 肺癌オルガノイドライブラリーを用いた肺癌シグナル経路異常の解明2021 · -
• 肺癌オルガノイドライブラリー統合解析による癌の不均一性の解明と新規治療標的同定2020 · -

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