Prefectural University of Hiroshima · Faculty of Bioresource Sciences · 教授

Research keywords生殖内分泌学・生殖生理学・卵子成熟・排卵機構・EGF様因子・ADAM17・SREBP・鉄代謝

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• Activation of PKA, p38 MAPK and ERK1/2 by gonadotropins in cumulus cells is critical for induction of EGF-like factor and TACE/ADAM17 gene expression during in vitro maturation of porcine COCs.
• Positive Feedback Loop Between Prostaglandin E2 and EGF-Like Factors Is Essential for Sustainable Activation of MAPK3/1 in Cumulus Cells During In Vitro Maturation of Porcine Cumulus Oocyte Complexes
• Miroencapsulation of canine sperm and its preservation at 4℃.
• Lipopolysaccharide (LPS) suppresses follicle development marker expression and enhances cytokine expressions, which results in fail to granulosa cell proliferation in developing follicle in cows.

• 鉄が制御する卵胞発育期の体細胞依存的な卵の代謝調節とエピゲノム制御の解明と応用
• プロゲステロン非活性化酵素依存的な優勢卵胞選抜とブタ、ウシの新規IVG法の開発
• 卵丘細胞から分泌されるプロジェステロンの減数分裂再開能に関する研究
• 時期特異的なADAM17基質特異性制御の解明による卵成熟誘導因子の探索

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