Ritsumeikan University · Organization for Integrated Science and Technology Research

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• Discovery of potent, selective, orally active benzoxazepine-based Orexin-2 receptor antagonists │ Bioorganic & Medicinal Chemistry Letters │ 21 (21),6414-64162011
• Synthesis of a Novel Series of Tricyclic Dihydrofuran Derivatives: Discovery of 8,9-Dihydrofuro[3,2-c]pyrazolo[1,5-a]pyridines as Melatonin Receptor (MT1/MT2) Ligands │ Journal of Medicinal Chemistry │ 54 (12),4207-42182011
• Molecular Cloning and Pharmacological Characterization of Monkey MT1 and MT2 Melatonin Receptors Showing High Affinity for the Agonist Ramelteon │ Journal of Pharmacology and Experimental Therapeutics │ 330 (3),855-8632009
• Effects of ramelteon (TAK-375) on nocturnal sleep in freely moving monkeys │ Brain Research │ 1027,59-662004

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