Ritsumeikan University · Faculty of Life Sciences / Graduate School of Life Sciences · 助教

Research keywordsextracellular vesicles・lysosome function・AMPK mTOR signaling・MEK ERK signaling・protein crystallography・structural biology・beta-glucosidase

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• MEK/ERK-mediated oncogenic signals promote secretion of extracellular vesicles by controlling lysosome function. │ Cancer science │ 113 (4),1264-12762022
• Asteltoxin inhibits extracellular vesicle production through AMPK/mTOR-mediated activation of lysosome function. │ Scientific reports │ 12 (1),66742022
• Insertion loop-mediated folding propagation governs efficient maturation of hyperthermophilic Tk-subtilisin at high temperatures. │ FEBS letters │ 595 (4),452-4612021
• Crystal structure of a GH1 β-glucosidase from Hamamotoa singularis. │ Protein science : a publication of the Protein Society │ 29 (9),2000-20082020

• がんにおいて細胞外小胞分泌を亢進するRAB27A発現調節機構の解明 │ 基盤研究(C)2023
• 普遍的に存在する三本鎖核酸構造が起こすゲノム不安定性 │ 若手研究2020
• RNA/DNAハイブリットを形成するDNA修復機構の構造基盤 │ 研究活動スタート支援2019
• 普遍的に存在する三本鎖核酸構造が起こすゲノム不安定性

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