University of the Ryukyus · Faculty of Medicine

Research keywordstRNA methyltransferases・2'-O-methylation・queuosine modification・mitochondrial tRNAs・mitochondrial RNA modifications・translational optimization・mitochondrial disease mutations

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• A transfer RNA methyltransferase with an unusual domain composition catalyzes 2'-O-methylation at position 6 in tRNA2025 · Teppei Matsuda, Yamagami Ryota, Aoi Ihara, Takeoi Suzuk, Akira Hirata, Hiroyuki Hori
• Glycosylated queuosines in tRNAs optimize translational rate and post-embryonic growth2023 · Xuewei Zhao, Ding Ma, Kensuke Ishiguro, Hironori Saito, Shinichiro Akichika, Ikuya Matsuzawa, Mari Mito, Toru Irie, Kota Ishibashi, Kimi Wakabayashi, Yuriko Sakaguchi, Takeshi Yokoyama, Yuichiro Mishima, Mikako Shirouzu, Shintaro Iwasaki, Takeo Suzuki, Tsutomu Suzuki
• Restoration of mitochondrial function through activation of hypomodified tRNAs with pathogenic mutations associated with mitochondrial diseases2023 · Tomoda, E. Nagao, A. Shirai, Y. Asano, K. Suzuki, T. Battersby, B. J. Suzuki, T.
• Mass Spectrometric Analysis of Mitochondrial RNA Modifications2021 · Yuma Ishigami, Tsutomu Suzuki, Takeo Suzuki

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