University of the Ryukyus · Faculty of Medicine · 助教

Research keywordshead and neck squamous cell carcinoma・human papillomavirus・laryngeal papilloma・sinonasal squamous cell carcinoma・p16 biomarker・photoimmunotherapy

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• p16 Overexpression in Sinonasal Squamous Cell Carcinoma: Association with Human Papillomavirus and Prediction of Survival Outcomes2023 · Hirakawa H, Ikegami T, Touyama M, Ooshiro Y, Higa T, Higa T, Agena S, Kinjyo H, Kondo S, Kise N, Tanaka K, Maeda H, Tamaki T, Wada N, Suzuki M
• 発症から2ヵ月経過し摘出に難渋した傍咽頭間隙金属異物例2023 · <p>We encountered a case with a very small metallic foreign body inside the parapharyngeal space which was removed via the transoral approach.</p><p>The patient was 36-year-old man living on a remote island. He visited the island’s clinic with a sore throat that he developed after eating fish soup. But his symptoms disappeared soon thereafter. However, the throat pain recurred after two months, and CT revealed a small foreign body inside the parapharyngeal space; the patient was immediately referred to our institution for removal of the foreign body. Since there was no abscess observed on the overlying skin and the location of the foreign body inside the parapharyngeal space could be well identified on the CT images, we attempted to remove it via a transoral approach without incising the skin. Intraoperative radiography and ultrasound were very useful to identify and remove the foreign body. However, the navigation system that we frequently use for operations of the nasal-paranasal sinuses was not as useful as we thought in this case.</p><p>The transoral approach is less invasive for the patient. If there is no inflammation or abscess in the affected area and the target foreign body can be identified before or during the operation, this approach may be of some advantage over the external incision method.</p>
• Human Papillomavirus Infection and EGFR Exon 20 Insertions in Sinonasal Inverted Papilloma and Squamous Cell Carcinoma.2023 · Hirakawa H, Ikegami T, Kise N, Kinjyo H, Kondo S, Agena S, Hasegawa N, Kawakami J, Maeda H, Suzuki M
• Biomarkers for Predicting Anti-Programmed Cell Death-1 Antibody Treatment Effects in Head and Neck Cancer.2023 · Tanaka K, Hirakawa H, Suzuki M, Higa T, Agena S, Hasegawa N, Kawakami J, Toyama M, Higa T, Kinjyo H, Kise N, Kondo S, Maeda H, Ikegami T

• ヒト乳頭腫ウイルス関連頭頸部癌の低酸素状態の分子機構に着目した低侵襲治療開発
• ヒト乳頭腫ウイルス関連頭頸部癌の低酸素状態の分子機構に着目した低侵襲治療開発
• 頭頸部癌の癌幹細胞を標的にした新規薬物治療の開発

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