Saitama Medical University · Faculty of Medicine / Graduate School of Medicine · 助手

Research keywordsRNA-binding proteins・TLS FUS・long noncoding RNAs・protein aggregation・arginine methylation・amyotrophic lateral sclerosis

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• Identification of Long Noncoding RNA Recognized by RNA-Binding Protein TLS/FUS: Purification of RNAs by Affinity Chromatography of GST-TLS
• Long noncoding RNA pncRNA-D reduces cyclin D1 gene expression and arrests cell cycle through RNA m6A modification
• m6A Modified Short RNA Fragments Inhibit Cytoplasmic TLS/FUS Aggregation Induced by Hyperosmotic Stress
• Biotin-Lys-His Blocks Aggregation of RNA-binding Protein TLS, a Cause of Amyotrophic Lateral Sclerosis.

• 分子化合物から細胞内構造体に至るメゾリンク-メゾスケール構造体の形成機構解析-2025
• 2018/10～2019/08 TLS/FUSのphase-separationにおける薬剤の効果2018 · 研究課題・受託研究・科研費

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