Saitama Medical University · Faculty of Medicine / Graduate School of Medicine · 教授

Research keywordscytosolic phospholipase A2・pulmonary fibrosis・collagen-induced arthritis・endothelial dysfunction・acute lung injury・prostaglandin E2・inflammatory bone resorption

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• An essential role of cytosolic phospholipase A2a in prostaglandin E2-mediated bone resorption associated with inflammation.
• Identification of novel cytosolic phospholipase A2s, murine cPLA2d, e, and z, which form a gene cluster with cPLA2b.
• Group IVA phospholipase A2 participates in the progression of hepatic fibrosis
• Acute lung injury by sepsis and acid aspiration: a key role for cytosolic phospholipase A2.

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