Saitama Medical University · Faculty of Medicine / Graduate School of Medicine · 講師

Research keywordstumor suppressor genes・DNA topoisomerase inhibition・cancer cell apoptosis・Akt signaling

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• ラボノートの書き方 ー記載上の留意点ー
• Isolation of a novel mouse gene,mSVS-1/SUSD2, reversing tumorigenic phenotypes of cancer cellsin vitro.
• von Willebrand factor type D domain mutant of SVS-1/SUSD2, vWD(m), induces apoptosis in HeLa cells.
• Leptosins isolated from marine fungus Leptoshaeria species inhibit DNA topoisomerases I and/or II and induce apoptosis by inactivation of Akt/protein kinase B.

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